PLITIDEPSIN AS A SUCCESSFUL RESCUE TREATMENT FOR PROLONGED VIRAL SARS-COV-2 REPLICATION IN A PATIENT WITH PREVIOUS ANTI-CD20 MONOCLONAL ANTIBODY-MEDIATED B CELL DEPLETION AND CHRONIC LYMPHOCYTIC LEUKEMIA

Abstract Background There is an urgent need for highly efficacious antiviral therapies in immunosuppressed hosts who develop coronavirus disease (COVID-19), with special concern for those affected by hematological malignancies.Case presentation Here, we report the case of a 75-year-old male with chronic lymphocytic leukemia who was deficient in Que

In this paper, 30 SFRC (Steel Fiber Reinforced Concrete) spindle specimens with different steel fiber contents were subjected to static loading tests and blast wave loading tests on spindle specimens with different steel fiber contents using a self-developed planar blast wave loading device (a new type of Developer Kit patent recognized by the Stat

We study data on perfumes and their odour descriptors-notes-to understand how note compositions, called accords, influence successful fragrance formulas.We obtain Tables accords which tend to be present in perfumes that receive significantly more customer ratings.Our findings show that the most popular notes and the most over-represented accords ar

This essay proposes a reading of the Anthropocene from the reconstruction of the energy imaginaries at the beginning of industrial civilisation.The transformations that took place in the energy matrix of productive processes, with the new social Adjustment Knob and geographical organisation of work derived from the use of fossil fuels, had their co

We study the role of international tribunals, like the International Criminal Court (ICC), Breast Pads as an effective way of reducing the number and/or gravity of crimes against humanity.The action of the ICC is directed against leaders that promote or tolerate these kinds of crimes, that is, political authorities, army commanders, civil leaders,